Arestat™ comprises two fundamentally different aspects of
our platform stabilization technology. Both utilize excipients
and buffers approved by the FDA and EMEA in an unconventional
manner to achieve the desired stability.
Both platform technologies are available for licensing for applications involving
therapeutic proteins, vaccines, medical devices and diagnostics.
Arecor collaborates with pharmaceutical and biotech
companies who are developing recombinant proteins and
vaccines for application in drugs, medical devices or
diagnostics. Arecor has developed Arestat™, a
smart stabilization technology, which enables the
formulation of labile proteins and vaccines as stable
aqueous or dry preparations even at high concentrations
or in the presence of ionizing radiation. As a simple
reformulation, the technology can be readily integrated
into existing manufacturing processes. Arestat™
does not involve the covalent modification of biologics
and uses only GRAS (Generally Regarded As Safe)
excipients approved by relevant regulatory authorities.
Arestat™ has a proven track record and has been
incorporated into a Class 3 medical device
(
Oxyzyme™)
approved in the EU and Canada. It is currently being
applied to several recombinant biologics in various
stages of development for administration via parenteral,
ocular and transdermal routes.